Gut Barrier Panel

KBMO has created a unique Gut Barrier Panel which in recognition that leaky gut occurs across a spectrum we have included the following gatekeeper markers: Candida, Zonulin, Occludin and Lipopolysaccharides (LPS). For each marker, we measure IgG 1-4 /C3d in addition to IgA 1 and 2.

Candida

We measure and use any candida overgrowth in the stomach/dysbiosis as a precursor to leaky gut occurrence.

Zonulin

Zonulin is a marker of intestinal permeability, otherwise known as leaky gut. If a patient has elevated Zonulin levels, the normal regulation of the tight junctions is compromised. This Zonulin marker is unique to KBMO please follow the link for more information: https://kbmodiagnostics.com/zonulin-test

Occludin

Occludin is a marker of tight junction stabilization and optimal barrier function. Elevated occludin indicates that the tight junctions are breaking down.

Lipopolysaccharides (LPS)

LPS is a major structural component of the outer membrane of gram-negative bacteria. Elevated levels of antibody against LPS may be indicative of Leaky Gut Syndrome and other gastrointestinal inflammatory diseases.